Listed Biotechnology Companies A
This Page Last Updated On 7/12/2024
1AD - AdAlta Ltd.
Company developing next generation antibody platform to treat serious diseases such as Idiopathic Pulmonary Fibrosis (IPF) listed in August 2016 at a value of $19 million. By the end of the year, shares had fallen 32% to $13 million. There was a 35% recovery in 2017 to $25 million as the company prepared for clinical trials after FDA granted orphan drug designation for IPF, but down 8% in 2018 to $27 million with raising of further funds. There was a 50% decrease in 2019 with company value at $19 million and new funds raised, changeover of CEO and new deal with GE Healthcare as well as Government funding for a diagnostic imaging product. There was a decrease and recovery in 2020 to $31 million (up 9% with funds raised) with the first clinical trial approved. There was a 36% decrease in 2021 to $24 million with extension of collaboration with GE Healthcare and new collaboration with Carina Biotech, which will be funded by a new facility provided by Victorian Government. There was a 49% decrease in 2022 to $13 million, with new collaboration started and a range of applications for lead product expanded. There was a 41% decrease in 2023 to $13 million, less than value on listing. There has been a 21% decrease in 2024 to $12 million with promising clinical trial result and new collaborative agreement signed. (21/11/24)1AI - Algorae Pharmaceuticals Ltd.
Rebranding of Living Cell Technologies (AX:LCT) occurred following shareholder meeting in September 2023. The company is intending to use artificial intelligence in drug discovery and development and has signed an MOU to this effect with University of NSW. There was a 10% increase in 2023 to $18 million with appointment of New Executive Chairman and discussions on link up with Dutch pharmaceutical and nutraceutical company. There has been a 20% decrease in 2024 to $13 million with NT Cell work from LCT gradually being phased out and new lead products generated by AI. (3/12/24)(AC8 - AusCann Group Holdings Ltd.)
Australian-based pharmaceutical company focused on development, production and distribution of cannabinoid-based medicines within Australia and internationally, acquired CannPal Animal Health (AX:CP1) for $17.5 million in 2021. Cannpal's CEO became head of the merged company. Cannpal shares transferred to AusCann in March 2021. There was a 58% decrease in 2021 to $36 million with trial in dogs showing positive results and registration of first dog product. There was significant changeover of board with new chairman. There was a 51% decrease in 2022 to $18 million with sale of WA facility and shift of business to New South Wales as well as departure of CEO. Shares suspended since end of August 2022 preliminary to announcement of proposed acquisition. Company has announced that it will partially divest its animal health assets and has sold its Wangara facility in WA. It has also signed a sales and distribution agreement and loan agreements with European Cannabis Corp. Fund raising in process but initial proposal withdrawn. Share suspension is likely to be concluded shortly. Company has expressed its intention to merge with European based cannabis manufacturer ECCPharm (formerly European Cannabis Corporation Ltd). The company was removed from the ASX official list on 28 August due to non payment of listing fees. (30/8/24)ACL - Australian Clinical Labs Ltd.
The company was originally formed through the integration of Healthscope's Australian pathology business in 2015, St John of God Health Care's pathology business in 2016, Perth Pathology in 2016 and acquisition of SunDoctors in 2021 at the time of an IPO when it was listed on the ASX. The company now has an extensive network of collection centres in all states, with associated laboratories and skin cancer clinics. The company expanded following its listing in 2015 and completed acquisition of Medlab Pathology, which expands its network in New South Wales and Queensland. The company has been profitable since listing with annual revenues over $500 million and a market value of over $1.2 billion at the end of 2021. There was a 52% decrease in 2022 to $601 million with financials improving. There was a further 3% decrease in 2023 to $583 million with signs that revenues are peaking. In March 2023, ACL made an off-market take-over offer for Healius Ltd (ASX:HLS) which has been rejected and was opposed by the ACCC. Due to this and the changes in the market, ACL withdrew its offer. There has been a 19% increase in 2024 to $696 million with financials down. (15/11/24)ACR - Acrux Ltd.
Acrux listed late September 2004 having already passed through two funding rounds. The technology was good and well-supported with good potential for commercialisation. On listing the price fell 10% immediately and stayed at around this level, followed by another 40% fall in April 2005 and some recovery. Announcement of positive Phase 3 trial results led to a 28% jump in 2006 which was wiped out in market drop of June followed by further rises as there were signs that the licensing stream was increasing with the licensing to Organon and milestone payments becoming significant. Market cap of $578 million following substantial fund raising (up 17% in 2006, a further 84% in 2007 but down 66% in 2008 and up 359% in 2009 following ostensibly positive analyst reports, conclusion of Phase III clinical trials with positive results and distribution agreement for Ellavie in Europe). There was a 62% increase in 2010 with announcement of substantial deal with Eli Lilly on AXIRON which pro vided substantial profit in FY2010, regaining of testosterone spray licence from Vivus and FDA approval for Axiron with associated milestone payment. There was a 19% decrease to $478 million in 2011 with financials showing that company revenues were up considerably, and profitability was also substantial as well as announcement of company's first dividend, launch of Axiron in the US by Eli Lilly, new veterinary product in Europe and introduction of Ellavie in Europe. There was a 38% increase in 2012 to company value of $658 million with improving outlook for Ellavie in European market and approval for sales of Axiron in Australia but final financial results for the year were seen as disappointing by the market and prices fell (eventually down 1% at $475 million). There was a 10% decrease to $426 million in 2013 possibly associated with the noticeable development in Acrux’s markets and signs that sales of Acrux product were levelling off. There was a further 32% decline to $291 million in 2014 and then a further drop of 22% in April (eventually down 55% to $192 million) due to FDA advice that testosterone products increased risk of stroke and heart attack in men (since discounted by FDA). This was impacting sales of Axiron but recovery in the second quarter of the year resulted in some increase in price and expectation of milestone payments as annual sales exceed $100 million (prices down 50% in 2014 to company value of $214 million and down 42% to $125 million in 2015 possibly due to uncertainty about FDA communications on risks of testosterone treatment and signs that Axiron sales are levelling off). There has been a 59% decrease in 2016 to $52 million with a US court ruling invalidating the Axiron formulation and application patents which would hit future sales of Axiron as generics arrive in market. There was a 52% decrease in 2017 to $25 million (less than cash holding) with sales projections declining but there was a jump in July with announcement of a release of a generic version of Axiron through Eli Lilly then a competitive one through Teva Pharma and Axiron sales are only down slightly from the year before although earnings have been severely impacted by a $10 million impairment. Termination of agreement with Eli Lilly on Axiron resulted in a 26% drop in September and Axiron was withdrawn from market in September. There was a 20% recovery in 2018 to $30 million with filing of Abbreviated New Drug Applications (ANDA) with FDA and intimations of other products indicating there is still life in the company. There was some dampening of prices towards to end of 2018 with patent challenge to one generic product and overall market downturn. There was a 6% increase in 2019 with company value at $32 million following settlement of patent dispute over new product and dossiers for new drugs presented to the FDA. There was a further 26% decrease in 2020 to $24 million until a new commercialisation arrangement was announced with TruPharma which may end the product development drought as well as a further agreement with Amring Pharma (eventually down 13% at $35 million following placement). There was a 39% decrease in 2021 to $28 million with new funds raised and new reviews with the FDA for new products although there is litigation on one. There was a 30% decrease in 2022 to $20 million. There was a 37% decrease in 2023 to $13 million with distributor buying out future royalties for Lenzetto®. There has been little change in 2024 at $13 million with launch of generic product in the US market. (16/111024)ACW - Actinogen Medical Ltd.
Another biotechnology company, previously called Australian Biogen, in Western Australia listing without clear justification in late 2007. Share prices fell over 90% in the year following listing indicating general market attitude. Company market cap was $3 million at the end of 2009 (down 82% in 2008 and up 16% in 2009 following 100% temporary jump based on wild speculation).There was a speculative 40% jump and a drop in 2010 to $1 million associated with speculation and a further quadrupling of prices associated with a new discovery that was some distance from commercialisation (up 20% to a market cap of $3 million by the end of 2010). There were unexplained oscillations in 2011 partly due to new discoveries that were some distance from being commercialised (eventually down 17% to $4 million). There was a further 80% fall to $1 million in 2012 apparently relating to concerns about lack of focus of the company with a round of fund raising significantly undersubscribed, staffing reduced and little spare cash. There was a 60% increase in 2013 with problems in raising funds and the withdrawal of a prospectus created some uncertainty. While one company has expressed interest in recapitalizing the company, the decision to close down the company laboratories resulted in a price fall (prices down 30% at $1 million in September 2013). Company took out a short-term loan to keep afloat and this coincided with exit of key players from the board. Re-engagement of chief scientists indicated there were moves to revive the company (shares even with company value of $1 million in November although regaining chief scientist doubled share price and subsequent consolidation and fund raising had little effect on price. Eventually up 10% in 2013, with company value at $4 million.) There was a 105% increase in 2014 to $22 million with recommencement of antibiotic program, new collaboration with Curtin University providing interesting results, acquisition of Edinburgh startup Corticrine and substantial renewal of board with a shift of the company to Sydney and a greater emphasis on medicine. There has been a further 36% increase in 2015 to $37 million with appointment of high-level advisory board to drive drug development and positive Phase I clinical trial. Company changed its name to Actinogen Medical Ltd in November 2015. There was an 18% decline in 2016 to $30 million and a temporary unexplained recovery (eventually up 18% at $44 million with FDA queries likely to delay a clinical trial). There was a 43% decrease in 2017 to $29 million with FDA and TGA approval for clinical trial and more funds raised. There was a 10% recovery in 2018 with company value at $50 million with more funds raised. There was a further 7% increase in 2019 to $54 million with increasing expectations for positive clinical outcomes but when the clinical trial results provided promising results but no significant effect, shares fell 67%. Eventually down 80% at $10 million but at end of September 2019, clinical results indicated a cognitive improvement in patients which resulted in a 370% rebound and eventually down 20% in 2019 at $40 million. There was a 42% decrease in 2020 to $30 million with a recent increase due to market promotion. There was a temporary 29% increase in 2021 to $39 million with FDA granting Rare Paediatric Drug Designation to Xanamem for treatment of Fragile X Syndrome but this disappeared (up 19% at $40 million). However the appointment of a new CEO resulted in a further jump followed by an unexplained 50% jump in late May possibly due to advances to clinical trials (eventually up 662% to $284 million). There was a 38% decrease in 2022 to $181 million with positive trial data having a positive effect. There was a further 78% decrease in 2023 to $51 million. There was a 214% recovery in 2024 to $187 million but in August announcement that clinical trial had shown clinical and statistical benefits but did not meet endpoint resulted in 60% share price fall (now up 41% at $95 million following review of clinical results reported previously). Fund raising successful and prices have rebounded. (7/12/24)ADO - AnteoTech Ltd.
Previously called Biolayer Corporation and SSH Medical, a medical equipment development company, which was restructured and acquired Queensland biotechnology company Bio-Layer. The latter company had already licensed its technology to a US diagnostics company and was working with a number of other international and local companies on developing new diagnostic products. Company had a market value of $3 million at the end of 2008 following substantial fund raising (down 57% in 2006, down 65% in 2007 and down 62% in 2008). A significant increase in revenues and reduction in losses suggested that company may have been undervalued but the company needed to improve its cash position for survival, and this was done with further fund raising. Name changed to Anteo Diagnostics in November 2008, but the company looked as if it might change its name to Anteo Technologies. New collaborative arrangements with a New Zealand company and a Malaysian company were negotiated. Prices down 65% to market cap of $3 million in 2009 indicating serious vulnerability of company despite fund raising. There was a 1,114% increase to $57 million in 2010 as a result of speculation following a licensing agreement with Bangs Laboratories which is already incorporating the Anteo technology in its product, but associated income is only just commencing. There was some relaxation in price in 2011 with recovery following announcements of further commercialisation (down 13% to $56 million). There was an increase to $63 million in 2012 with signing of new technical licensing agreement but shares fell below par with first signs of commercialisation bearing fruit (down 15% at $49 million). Half yearly financials indicated substantially improved financials with further improvements likely but with little initial significant effect on prices. Signature of agreement with BBI Solutions led to an increase (eventually up 154% in 2013 with company value at $130 million). There was a 25% decrease in 2014 to $101 million with launch of new product and new collaboration. There was a further 32% decrease in 2015 to $76 million with first signs of revenues increasing, a new distribution deal in Japan, new development agreements signed, a new product launched, new collaboration with IMRA, acquisition of Belgian diagnostics company and extension of arrangements with Sigma-Aldrich. Prices depressed by fund raising for Belgian acquisition which was completed. New funds raised and 50% decline in share price in 2016 resulted in company value of $46 million with new investment arrangement, speculation over battery technology, retirement of CEO, and new products. There was a 78% decline in 2017 to $10 million following expected announcement of sale of Belgian diagnostics subsidiary to remove substantial debt. However, announcement of positive assessment of battery technology resulted in some recovery and new CEO was hired (eventually down 61% at $18 million). Company value was given a boost with the announcement in December 2017 of commencement of a lithium battery project to push commercial discussions. There was a decline and recovery in 2018 to $20 million (up 6%) with another change of CEO and Chairman and some progress on lithium battery technology. There was an 29% increase in 2019 to $33 million, with promising developments for diagnostics in China, appointment of yet another CEO who has just been replaced, new funds raised and new collaborations in the US and Spain. Company changed its name from Anteo Diagnostics to AnteoTech in November 2019. There had been a 5% increase in 2020 to $38 million with speculation affecting prices, a new agreement with Merck, new funds raised and advances in battery and diagnostic technology. The announcement in July 2020 of a new test for Coronavirus antigens resulted in a 400% jump in prices to $187 million (eventually up 377% at $196 million). There was a 190% increase in 2021 to $602 million when a customer using its technology, Ellume, gained major contract to supply consumer Covid tests to the US as well as participation in major Australian battery development project and increasing interest from battery collaborators. There was an 81% decrease in 2022 to $113 million with replacement of CEO and chairman and positive battery developments but delay of key study has affected prices. There was a 39% decrease in 2023 to $79 million with new agreements signed on battery technology. A recent rebranding of the company resulted in a 75% temporary share price increase. There has been a 47% decrease in 2024 to $51 million with securing significant grant and raising funds and achievement of technical milestone in anode design with commercial assessment of product and first commercial order. (26/11/24)ADR - Adherium Ltd.
New Zealand digital health company developing technologies to address optimal medication and optimise remote patient management in chronic disease successfully raised $35 million and following listing on 26 August 2015, company value at end of 2015 was $92 million (up 29%). There was a 63% decline in 2016 to $41 million and a further 58% decline in 2017 to $17 million with a new CEO appointed to drive sales but company value is little more than cash holding. There was a 63% decrease in 2018 to $6 million with funds raised, new marketing approaches being used and restructuring to reduce costs. There was a 24% decrease in 2019 to $5 million with raising of new funds and a new collaboration to develop an Adherium platform for treatment. There was little change in 2020 with company value at $19 million with raising of substantial funds and better prospects in US market. There was a 61% decrease in 2021 to $24 million with substantial funds raised and changeover of CEO. Another listed company, Respiri, made a takeover bid for the company but this bid has lapsed. There was a 64% decrease in 2022 with company value at $20 million following substantial fund raising, revenues increasing and FDA clearance. There was a 7% decrease in 2023 with company value at $19 million and outlook for commercialisation improving with new partnerships. Company completed 15:1 consolidation. There has been an 79% decrease in 2024 to $9.1 million with another changeover of Managing Director, new raising of funds and several strategic partnerships on patient monitoring. (5/12/24)AFP - AFT Pharmaceuticals Ltd.
New Zealand pharmaceutical company founded 25 years ago and listed on ASX in late 2015 at a value of $271 million. The company has expanded internationally and gains significant income through licensing and royalties. There was a 14% decrease in 2022 to $357 million. There was a 4% decrease in 2023 at $341 million with distribution deals signed and FDA approval of lead drug as well as improving financials and collaborations on new products. There has been a 24% decrease in 2024 to $259 million with financials improved but outlook problematic. (27/11/24)AGN - Argenica Therapeutics Ltd.
Company founded in late 2019 to develop and commercialise a novel drug developed at University of Western Australia. The arginine rich peptide has neuroprotective properties. Company listed in mid 2021 at an indicative value of $14.6 million. Value of company increased four fold between listing and the end of 2021. There was a 46% decrease in 2022 to $39 million with Phase 2 clinical trial in planning. There was a 13% increase in 2023 to $43 million following raising of funds. There has been a further 29% increase in 2024 to $85 million with clinical trial progressing. (3/12/24)ALA - Arovella Therapeutics Ltd.
Formerly Suda Pharmaceutical (name change in October 2021) and Eastland Medical Systems then focussing on sub-lingual drug treatment for malaria. Another company offering an alternative delivery system for drugs. Company has also acquired oral spray drug delivery technology from NovaDel and was applying this to treatment of migraine and nausea and oral delivery of sildenafil. Shares down 23% in 2014 at $58 million and a further 54% in 2015 to $31 million despite a new collaborative agreement with Amherst and new funds raised. There was a 26% decline in 2016 to $23 million. There has been a decline and recovery and down 20% in 2017 with company value at $20 million and trading was suspended in February 2017 in association with litigation with HC Berlin Pharma. Announcement of licensing arrangement with Teva Pharma had little impact on value but increasing profile of the company in the media did. Company changed name to Suda Pharmaceuticals Ltd in November 2017. There was a 63% decrease in 2018 to $15 million with sale of non-core subsidiary and loss in litigation with payment of A$2.5 million over 3.5 years occasioning a 1:1 rights issue which has raised substantial funds. A recent speculative 100% jump in share price probably resulted from new commercial deal completed for migraine treatment and there may be further speculation associated with development of a cannabidiol spray. There was a 61% decrease in 2019 to $8 million with announcement of TGA denial of marketing approval for Artimist oral spray (which led to suspension of the program), the appointment of a new Chairman and CEO, reorganisation of the Board, new commercialisation approaches and raising of new funds as well as a 25:1 share consolidation in late November 2019. There was a further 53% decrease in 2020 to $4 million with fund raising completed but announcement in July that the TGA had approved ZolpiMist resulted in a 240% boost (eventually down 31% at $15 million). There was a 3% decrease in 2021 to $19 million with licensing in of new technology and raising of funds to support its development. There was a 41% decrease in 2022 to $15 million with a recent jump associated with preclinical development of a treatment with Imugene and discontinuation of Oromist development to concentrate on new therapy developed with Imugene and new key technologies licensed in. There was a 409% increase in 2023 to $100 million with new funds raised for the new therapy and speculation about the therapy increasing prices. There has been a 64% increase in 2024 at $191 million with collaboration with Imugene discontinued. (2/12/24)AN1 - Anagenics Ltd.
Previously called Medical Therapies which listed without a clear justification in 2005. By 2009, market cap had fallen to $6 million with speculation over first new drug product under development and appointment of new CEO/MD which was not supported by shareholders. The larder appeared to be rather bare putting prices under downward pressure, so it was not surprising that the company acquired a patent portfolio from Japan covering midkines to add blue sky potential in 2008. Company name was changed to Cellmid in November 2009. Company market cap at $7 million in October 2010 (down 6% in 2009 and down 38% in 2010) with new funds raised and licensing opportunity found. There was a tripling of the share price in November 2010 without explanation and shares then declined to a loss of 12% in 2010 with a market cap of $10 million. There was a significant rise in 2011 associated with preparations for clinical trials (eventually down 47% at $7 million following conversion of convertible notes and with further funds to be raised with only a 25% take up in fund raising at end of 2011). Prices declined 6% in 2012 with company value of $8 million following TGA approval for new hair product line which had just been launched and earning income and new funds raised. There was a 93% rise in 2013 to $21 million associated with new funds raised and new licensing deal with Fujikura as well as new shares in Pacific Edge and new agreements in Japan and China. There was little change in 2014 (down 10%) with company value at $19 million with manufacturer of first antibody therapeutic chosen and new licensing deals. There was a 19% decrease in 2015 to $17 million and a recovery to $22 million (down 8%) with announcement of positive clinical trials with hair products, new funds raised and a move towards the US market. There was an 8% increase in 2016 to $28 million with funds raised, significant sales by subsidiary in Japan and launch of product in the US. There was a 2% decrease to $29 million in 2017 with revenues increasing and share consolidation having a small positive effect on value and there was a 45% decrease in 2018 to $24 million with signing of new distribution agreements, new funds raised and signs that retail sales were increasing. There was a further 21% decline in 2019 to $21 million with revenues and costs increasing but a positive sales event in Japan did not succeed in lifting share prices. There was a 55% decrease in 2020 to $10 million and this was more than reversed when the company announced a deal for supply of a rapid Covid-19 diagnostic. This resulted in a 200% price jump which then dissipated (eventually down 50% at $14 million). There was a further 48% decrease in 2021 to $13 million with funds raised but revenues appeared to have peaked. Company sold its biotechnology subsidiary Lyramid and became a predominantly consumer health business but as such was in the process of acquiring BLC Cosmetics to expand its profile in the anti-ageing and beauty health sector. Associated with this, company changed its name to Anagenics (AX:AN1) in December 2021. There was a 58% decrease in 2022 to $6 million with changeover of chairman and managing director/CEO and new director with a refocussing of the company, divestment of Japanese subsidiary and acquisition of skincare company USPA. There was a 24% decrease in 2023 to $7 million with new funds raised, new CEO appointed and acquisition of customer to accelerate growth. There has been an unexplained 58% decrease in 2024 to $3.7 million with funds raised and reorganisation of company with change of CEO and some possibility of licensing of midkine technology. Company is currently in voluntary suspension due to process of restructuring. (24/11/24)(ANP - Antisense Therapeutics Ltd.)
Following its listing 1in 2001, shares drifted down 75% as it was known from the outset that commercialisation of the company's products would take some time. The shares were given a fillip in August 2003 as part of an overall boost in biotech stocks and, surprisingly, prices remained high for a while before gradually declining. However, the announcement in March 2005 of complications with a competitor's product directed at the same target led to a sharp 60% drop and some temporary recovery associated with reinitiation of clinical trials, although a proof of concept study which indicated limited effect reversed this (down 71% in 2005). In 2006, recommencement of a clinical trial and a proposal for refinancing of the company resulted in an improvement (100% in five months to end January 2007) and prices were the same as at the beginning of 2006. There was a modest 5% price rise in 2007. In 2008 there was a 100% increase due to the deal with Teva Pharmaceuticals and positive trial results (eventually down 17% in 2008). The market cap of the company was $29 million in early 2010 (up 57% in 2009 and down 11% in 2010) which we considered was high in view of cash reserves of $3 million and was driven by future expectations as Teva had made milestone payments. When Teva advised in March 2010 that it was discontinuing development and termination of the licence, there was a steep fall in value with some recovery to $8 million (down 87% in 2010) on expectation of new licensing opportunities and new funds raised and up 229% in 2011 at $23 million with excessive speculation over early stage clinical trials. There was a decline to $16 million in 2012 (down 52%) with new funds raised but no explanation for a temporary rise which ended when agreement with Afandin lapsed. There was a 36% increase to $22 million in 2013 following developments on clinical trials and share consolidation having little impact on company value. There was a 40% decline in 2014 with company value at $14 million with new fund raising completed and company searching for partnership deals to assist future development. There was a short term 60% increase in 2015 to $28 million with signing of licensing agreements in Sweden and the Netherlands and licensing revenues providing some profitability This dissipated to a degree (eventually down 21% at $13 million). There was a further 49% decline to $6 million in 2016 with announcement that licensing partner Strongbridge Biopharma was terminating its licence to ATL1103 and new application being sought for ATL1102 in multiple sclerosis. There was a 33% decrease in 2017 to $4 million with positive clinical trial results and slow progress to next trials. There was a 29% decrease in 2018 to $6 million following new fund raising and commencement of new clinical trial. There was a 200% share price jump to $22 million in October (eventually up 8% to $10 million). There was a further 88% increase to $21 million in 2019 due to speculation over a trial in process and raising of new funds. Preliminary results for the clinical trial were positive leading to a further 64% jump in prices (eventually up 246% in 2019 to $42 million.) There was a 44% increase in 2020 to $75 million with new funds raised, positive clinical trial results and orphan drug designation gained. There was a further 50% increase in 2021 to $130 million with more positive data on applications of products and new funds raised. There was a 50% decrease in 2022 to $65 million. There has been a 43% decrease in 2023 to $50 million with replacement of retiring Managing Director in place and funds raised. The company changed its name to Percheron Therapeutics (ASX:PER) in early 2024. (6/1/24)ANR - Anatara Lifesciences Ltd.
Company reviving an old product from pineapple stems for treating gastrointestinal diseases in animals and humans listed towards the end of 2014. Second trial in pigs underway and shares have shown a steady increase since February 2015 (up 223% at $51 million in 2015) with second positive trial in pigs. There was a further 1% increase to $52 million in 2016 and down 9% in 2017 with company value at $47 million. However, announcement of increased interest in a commercial agreement by Zoetis resulted in a 37% jump in August 2017 (eventually up 65% at $85 million). There was a 73% decrease in 2018 to $23 million with the FDA approving the Human Food Safety Dossier on Detach®, at global licensing agreement signed with Zoetis and the retirement of Executive Chairman and other directors. There was a 28% decline in 2019 to $16 million with appointment of new CEO and a further 41% drop when Zoetis terminated its Detach licence (down 48% at $12 million in 2019). There was a 29% decrease in 2020 to $12 million following fund raising. (The cause of a speculative 45% price jump in February remains unclear but may be related to prospects for a clinical trial.) There was an 18% decrease in 2021 with company value at $10 million. There was a further 76% decrease in 2022 to $4 million. with clinical trials starting, inconclusive results in animal trials, departure of CEO, changeover of COO and new fund raising completed. There was a 32% decrease in 2023 to $4 million with positive clinical results. There has been a 136% recovery in 2024 to $11 million with promising clinical data. (5/12/24)ARX - Aroa Biosurgery Ltd.
Company listed in July 2020 as a company that develops, manufactures and distributes medical and surgical products to improve healing in complex wounds and soft tissue reconstruction. There has been a 15% decrease in 2024 to $243 million with revenues increasing. (7/12/24)
AT1 - Atomo Diagnostics Ltd.
Company founded in 2010 as a medical device company commercialising in vitro diagnostic products with differentiating aim to develop more user-friendly diagnostic solutions initially in HIV area. Listed in April 2020 at a value of $112 million and soon gained TGA approval for Covid-19 antibody test. Since listing, shares increased 53% to company value of $172 million in 2020. There was a 3% decrease in 2021 to $170 million with jumps associated with FDA approval for a Covid test incorporating Atomo technology and increasing market interest in the company. There was an 82% decrease in 2022 to $31 million with latest financials indicating increased sales and reduced losses and more marketing management taken on. There was a further 59% decrease in 2023 to $14 million. There has been a 9% decrease in 2024 to $13 million with new orders for company diagnostics and the latest Federal Budget supporting HIV self testing which will use Atomo's test. (19/11/24)ATH - Alterity Therapeutics Ltd.
Before changing its name from Prana Biotechnology to Alterity Therapeutics in April 2019, Prana suffered from being promoted too soon and endured the consequences of lack of stock market faith. Lack of success in developing lead compounds led to price oscillations without clear outcomes in the decade to 2015. With further promotion, value peaked at $447 million in 2014. However, failure of a clinical trial in 2015 resulted in a steep fall in prices with company value reaching $18 million in 2018. The advent of a new investor in 2019 resulted in some recovery (up 48% to $42 million) and change of name to Alterity Therapeutics has led to a repositioning of the company in the market. Shares were down 39% at $17 million in 2019. There was a 55% increase in 2020 to $63 million with some relief from NASDAQ compliance due to Covid-19 crisis, new funds raised and progress on FDA clearance. There was a 32% decrease in 2021 to $51 million. There was a 52% decrease in 2022 to $24 million with IND approval for Multiple System Atrophy treatment . There was a 40% decrease in 2023 to $17 million with phase 2 trials starting, new supply agreement for Europe and new fund raising to start trials. There has been a 14% decrease in 2024 to $32 million with raising of more funds and conclusion of clinical trial. (7/12/24)